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Serious adverse events (SAEs) were defined as: 1) critical or life-threatening complications

namely, acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3, which are involved in the biosynthesis of phosphatidylethanolamine

However, recent studies have found that the expression of GPX4 is significantly decreased in the early and middle stages of MI [44], suggesting that MI may lead to ferroptosis in myocardial cells

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21,32 In addition, iron is important for normal mitochondrial function, ER stress, DNA impairment and repair, and other cell survival-related enzymatic reactions