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For a general deficiency, many protocols start with 100 mcg injections daily or every other day for the first week

10.1111/j.1872-034X.2008.00419.x 33 LiS.HongM.TanH.-Y.WangN.FengY

Not a single commercial product exists after a century of trying

10.1016/j.jtcvs.2009.09.025 J Thorac Cardiovasc Surg

For instance, transcription factor TTF1 (also called NKX2.1), which is used and necessary in thyroid and lung normal cells proliferation is still used and necessary for pulmonary and thyroid cancer cell lines growth [180]