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Furthermore, it decreased the expression of -SMA and induced apoptosis in HSCs, which contributed to the mitigation of fibrosis progression in vivo

LUAD, lung adenocarcinoma

doi: 10.1186/s12974-014-0189-0 122 ThomsonARPasantaDArichiTPutsNA

5 Summary and perspectives 5.1 Integrative summary: RSS as multilevel immune coordinators This review systematically dissected RSS immunoregulatory mechanisms across innate and adaptive immunity, establishing RSS as central coordinators integrating redox metabolism with inflammatory programming and antigen-specific responses