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(PubMed) Spence JD

Furthermore, pro-inflammatory cytokines which are generated from immune cells, such as TNF- and IL-1, are raised during SIRS to encourage the recruitment of immune cells into the brain parenchyma

CLINICAL STAGE OF ACETAMINOPHEN POISONING GENERAL MANAGEMENT Acetaminophen poisoning is an emergency because the longer the poison stays, the more the distribution and the worse the outcome