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Limiting the GSH formation by inhibiting system x c - is a promising approach to kill tumor cells due to the excessive active metabolism and sustained oxidative stress [43]

In an assay mixture 100 g protein was incubated in a 1 ml solution containing 5 mM manganese chloride or MnCl 2 , 0.1 mm DTT, 0.1 mM p-coumaric acid, 0.05 mM NADP(H), 30 mM sodium acetate buffer (pH 7.5) and incubated under dark

Lipid biosynthesis predominantly occurs in the liver and adipose tissue, utilizing acetyl-CoA as the central substrate

Chronic inflammation and the hallmarks of aging

This data can be accessible at: Abbreviations ADA: American Diabetes Association ALP: Alkaline phosphatase BMC: Bone mineral content BMD: Bone mineral density CDC: Centers for Disease Control and Prevention DAVID: Database for Annotation, Visualization and Integrated Discovery DXA: Dual-energy X-ray absorptiometry FAD: Flavin adenine dinucleotide FMN: Flavin mononucleotide GO: Gene Ontology GSH: Reduced glutathione GSSG: Oxidized glutathione KEGG: Kyoto Encyclopedia of Genes and Genomes MEC: Mobile Examination Center MET: Metabolic equivalent task NHANES: National Health and Nutrition Examination Survey PA: Physical activity PPIs: Protein-protein interactions RCS: Restricted cubic spline References Ensrud KE, Crandall CJ, Osteoporosis