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While some free radical production is normal and even necessary for immune function and cell signaling, excessive amounts lead to oxidative stressa condition linked to aging, inflammation, and numerous diseases

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Dietary patterns frequently observed in patients with CD, particularly after initiation of a gluten-free diet, are often characterized by a higher intake of fats and simple sugars and a lower intake of fiber, which can further promote intestinal permeability, dysbiosis, and low-grade systemic inflammation, thereby contributing to insulin resistance, dyslipidemia, and endothelial dysfunction ( Chronic immune activation in CD also causes oxidative stress (OS)

Biological Importance of Zinc and Cardiac Inflammation Context Zinc (Zn) is an essential trace element found in the human body at trace levels

This tolerance allows for travel and temporary storage situations when refrigeration isn't available