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The slide images were captured by an inverted microscope and the average optical density (AOD) was measured using Image J 1.53t software

*Correspondence: Jihang Chen, [email protected]

331 iNOS (inducible nitric oxide synthase) produces nitric oxide (NO) during inflammation, modulating signal transduction

Participants were seated in front of a computer screen at 90 cm distance and were instructed to keep the same right upper limb position (i.e., upper arm and forearm at 90 angle and hand extended) whenever using the dynamometer (see Supplementary Figure 3A)