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NO-ASA is thought to exert its anticancer effects by an esterase catalyzed release of an electrophile quinone methide (QM) intermediate that selectively reacts with and depletes intracellular GSH [15, 22]

This view dominated for nearly a century

Alcohol 49, 773779

J Proteomics (2016) 145:197206

807 The long alkyl chain of 389 (Figure 94) promotes the assembly of siRNA/carrier, can form a stable self-assembled complex with siRNA, and increases the stability of the complex through hydrophobic interactions