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Inactivation of GPX4 results in the aberrant accumulation of lipid peroxides, thereby inducing ferroptosis (16)

Precautions/Side Effects As with any medication, consult your healthcare provider for possible contraindications and interactions with other medications you may be taking

Traditional Chinese medicine ZHENG and Omics convergence: a systems approach to post-genomics medicine in a global world

What differs is the fate of the hydroxyethyl group bound to thiamine pyrophosphate: in the reaction catalyzed by pyruvate dehydrogenase, this group is transferred to the next enzyme in the sequence, dihydrolipoyl transacetylase, whereas in the reaction catalyzed by pyruvate decarboxylase it is converted into acetaldehyde