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When functioning as an HDAC inhibitor, butyrate treatment increases histone H3 lysine 9 acetylation, upregulating transcription of glucose metabolism-related genes like glucose transporter type 4 (GLUT4), monocarboxylate transporter 1 (MCT-1) [68], consequently enhancing glucose uptake with possible secondary stimulation of fatty acid synthesis in muscle cells

Bernecker et al., 2011

If you experience symptoms of an allergic reaction, such as severe itching, redness, swelling or difficulty breathing, discontinue use immediately and seek medical attention

Serum liver tests should be performed prior to therapy and at frequent intervals thereafter, especially during the first six months [seeWarnings and Precautions (5.1)]

Moreover, Cu serves as an important cofactor for enzymes such as CuSOD, cytochrome C oxidase (99)