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10.3892/ol.2016.5354 147 LiuZ.DouW.ZhengY.WenQ.QinM.WangX.et al (2016b)

studied Elsholtzia ciliata Hylander ethanol extract (ECE) for its anti-inflammatory and antifibrotic effects on renal interstitial fibrosis

At a minimum, this approach would help to ensure that if antigen-specific T reg cells lost suppressive activity, the ectopically expressed FOXP3 would minimize the activity of the resulting effector T cells