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A higher or lower MCV may indicate specific conditions, such as vitamin deficiencies or dehydration

Int Clin Psychopharmacol 2003;18:61-71

Vitamin B5 is a precursor to Coenzyme A (CoA), a critical molecule in the energy metabolism pathway

(PubMed) Caldwell KL, Makhmudov A, Ely E, Jones RL, Wang RY

Treatment with HU and LC reduces frequency of blood transfusions, in hospital days, and number of painful episodes per year, as such it cuts the economic burden of SCA in a given society