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Next, we started to increase the temperature of the measurement chamber from 25 C to 50 C

Further evidence of a role for oxidative stress in glaucoma is the significant serum increases in metabolites from nitric oxide production [7] and high plasma levels of the lipid peroxidation product malondialdehyde observed in glaucoma patients compared to control [8]

However, these biomarkers have several limitations: they are not liver-specific, they do not reliably predict DILI outcomes, and they provide limited mechanistic insights into the underlying processes of liver injury

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Jpn J Clin Chem 35(3):280294 Kamata T, Akasaka K, Ohrui H, Meguro H (1994) Fluorometric assay of glutathione peroxidase activity in liver and plasma with N-(9-acridinyl) maleimide