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6 The Many Complications of Chronic Kidney Disease CKD is associated with a wide range of significant health complications, including 64 : Cardiovascular Disease Cardiovascular disease, particularly advanced cardiovascular disease, is associated with a significantly elevated risk of various cardiovascular problems, such as hypertension (high blood pressure), arterial calcification (calcium buildup in the arteries), heart failure, valvular disease (damaged heart valves), and atherosclerosis

Genetic deficiencies of transporter activity represent the only known forms of primary carnitine deficiency [27]

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Rare: Dyspepsia, heartburn (5)

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