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The levels of Glu in neurons are influenced by extracellular glutamate concentrations and its conversion in astrocytes

Chang Y, Wei W, Zhang L, Xu HM

10.1016/S1532-0456(02)00078-9 14 DahlbergA

These in vitro mechanisms were recapitulated ex vivo, as observed by the strong correlations of ex vivo 15LO1 protein with intracellular GSH ( r = 0.68, P = 0.005) and GSH:GSSG ( r = 0.62, P = 0.014) in freshly brushed HAECs (Figure 3F)

Selection of remedial actions should prioritize protection of drinking water sources and human health, with consideration of other objectives (such as reducing risk to ecological receptors and environmental resources, liability, source area mass, mass flux, generation of PFAAs from precursors)