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These findings suggest that while SAR provides partial neuroprotection after 57 weeks of treatment, targeting higher-order cognitive deficits may require longer SAR therapy to restore hippocampal and cortical connectivity, synaptic integrity, and excitatory/inhibitory balance

As an intracellular selenium protein, GPx4 can directly reduce the production of peroxide phospholipids in the cell membrane [16]

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This condensation is catalyzed by glutathione synthetase

The preventive evaluation revealed that the serum inflammatory markers such as IL-8 and IL-6 were markedly reduced