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Inadequate energy intake, particularly if carbohydrate consumption is very low, may result in feelings of weakness, shakiness, or light-headedness that patients may interpret as jitteriness

Extrinsic aging is predominantly influenced by sun exposure (photoaging), although smoking and pollution also play a role.1 Intrinsic and extrinsic aging overlap in clinical practice.1 Demand for strategies to mitigate the signs of skin aging is high.2 Recent studies suggest that regular exercise, apart from improving quality of life and reducing the risk of mortality and chronic disease,2 might also reduce the thickness of the stratum corneum and improve dermal thickness and collagen content.3 Diet is also important, with a number of studies highlighting its role in the prevention of aging

doi: 10.1126/scitranslmed.aah6733 32 NomuraTMusialTFMarshallJJZhuYRemmersCLXuJet al

[DOI] [PubMed] [Google Scholar] 73.Faissner S, Plemel JR, Gold R, Yong VW

It is not for human consumption