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The main causes of mitochondrial swelling are collectively known as direct inner membrane damage induced by oxidative stress and calcium overload in the mitochondrial matrix, forcing an increase in membrane pore permeability and a consequent alteration of osmotic pressure between the outer and inner membranes [7, 8]

Tannins, also known as Polymer Phenolics, can be of two main types, i.e

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At standard supplemental doses (600-1800mg daily), NAC is well-tolerated by most people