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In parallel, large-scale applications remain constrained by production costs and the limited availability of natural compounds

Aliquots of 25 L of the reaction mixtures were plated onto chocolate agar in duplicates at the beginning of the assay (t 0 ) and again after incubation at 37 C for 30 min (t 30 )

We generated 100 structural models of the FOXO4 FH bound to the p53 TAD2 , starting with the 3D structure of FOXO4 FH (PDB: 1E17 55 ) and the p53 TAD2 domain as an elongated chain

A MOF layer loaded with SNPS is then used as a coating to form the shell (SNP@MOF-UCNP) (Fig

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