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Donghui Na, Zechen Zhang, Junyan Gao, Ying Guo, Guohui Zhang and Jiming Kong prepared the figures, wrote, corrected, amended, and approved the final edition of the manuscript

Apocynin is a plant drug derived from Picrorhiza kurroa

Real-Time PCR To quantify mRNA levels of OA and apoptosis-related gene expression, total RNA was extracted from the cells for in vitro and cartilage for in vivo according to the manufacturers instructions (iNtRON Biotechnology, South Korea)

But in other parts of the globe, it's regularly eaten at meals or used as medicine

Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma