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Immune system disorders: To suppress the immune system in conditions like lupus or rheumatoid arthritis

In severe cases, a deficiency can even lead to a swollen and inflamed tongue and mouth, known as glossitis

85011433) were purchased from the European Collection of Authenticated Cell Cultures (ECACC) and were cultured in DMEM (Sigma-Aldrich) supplemented with 10% FBS, 1 mM HEPES, 100 mM sodium pyruvate, and 1x Tryptose Phosphate Broth (Gibco)