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Therefore, arginine metabolism and subsequent polyamine biosynthesis play pivotal roles in regulating CD4 + T cell differentiation in disease settings

Oral ivermectin disposition is affected in horses by concomitant administration with antihistamines, including fexofenadine and cetirizine, which is in line with the well-known transporter-mediated interactions with systemic exposure (94, 95)

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This dual action is especially relevant for immunocompromised patients

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