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Additionally, the viral protein ORF3a recruits Kelch-like ECH associated protein 1 (Keap1) to degrade NRF2, diminishing the cell's oxidative stress defense and promoting ferroptosis (109)

FDA Access Data Shankar, A., et al

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Autophagy process is related to the maintenance of cellular homeostasis, and its dysregulation could lead to the development of several aging-related pathophysiological diseases [11]

Results Bioinformatics analysis The cDNA sequence of HrGSTm1 (OQ790160) contains a 672-b open reading frame (ORF) that potentially encodes 233 amino acids (aa) (Fig