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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

It should not be prescribed concurrently with monoamine oxidase inhibitors (MAOIs) or other medications that significantly alter serotonin pathways due to the risk of serotonin syndrome

Patients should talk to their oncologist about their own risks

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Now, the timing may be different based on how low your B12 levels were to start with