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Flavokavain A was shown to induce G2/M arrest in a panel of cancer cell lines, including breast cancer cell lines (MDA-MB231 at 65 M) [22], high-grade bladder cancer cell lines (T24, UMUC3, TCCSUP, 5637, HT1376, and HT1197 at 40 M) [122] and prostate cancer cells (PC3 at 50 M) [123]

The amounts of TB-500 referenced in the literature are roughly an order of magnitude larger than those referenced for BPC-157 a difference of scale, not a rounding error

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This can make diagnosis difficult

The open-label design of the GOLDEN-5 study may be perceived as a potential limitation to making comparisons between the 2 treatments