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Discovering CRISPRCas off-target breaks

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The oncogene c-Myc enhances MAT2A expression by promoting the degradation of SIRT4, thereby amplifying the oncogenic output of methionine metabolism [92]

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10.1001/jamanetworkopen.2021.40644 184 ZhaoH.LiY.JinH.XieL.LiuC.JiangF.et al (2010)

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