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These peptides have a significantly reduced capacity to crosslink IgE, and consequently, they do not activate mast cells or basophils, reducing the risk of allergic reactions [158, 159]

Ethics declarations Ethics Approval All experiments involving animals were carried out in accordance with NIH guidelines and were approved by the University of Selcuk Animal Care and Use Committee (Protocol Number: 201828)

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Slides were deparaffinized in xylene, rehydrated through a graded ethanol series, and subjected to antigen retrieval in citrate buffer (pH 6.0) using microwave heating