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For a summary of nonFDA-approved agents that have been used to help people cut down or stop their use of alcohol (along with their mechanisms of action, adverse effects, and evidence for efficacy), see Table 2

In cases of suspected cobalt hypersensitivity, an intradermal test dose should be administered

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Its capacity to accelerate antidepressant onset, improve cognition, enhance sleep architecture, and reduce biomarkers of neuronal injury positions it as a neuroprotective adjunct rather than a primary antidepressant monotherapy