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Repeated punctures with a contaminated needle introduce microbes that proliferate during storage, even at refrigerator temperature

As summarized by Stier, Vos, and Kenley in 2013, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, while the compound's tolerability profile remained comparable to placebo

In other research, obese mice on a high-fat diet given 5-Amino-1MQ had roughly a 5% reduction in body weight in just 11 days and improved insulin sensitivity

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