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Disclosures: Raj Prasad: Nothing to Disclose, Richard Bell: Nothing to Disclose, Nawaz Safdar: Nothing to Disclose, Hauke Lang: Nothing to Disclose, Alfredo Guglielmi: Nothing to Disclose, Thomas van Gulik: Nothing to Disclose, Pim Olthof: Nothing to Disclose, Raj Prasad: Nothing to Disclose 721 A NUCLEOSOME SWITCH PRIMES HEPATITIS B VIRUS INFECTION Nicholas Prescott 1 Andres Mansisidor 2 Yaron Bram 3 Christine Lim 3 Viviana Risca 2 Yael David 4 Robert Schwartz 5 , 1 Memorial Sloan Kettering Cancer Center, 2 Rockefeller University, 3 Weill Cornell Medicine, 4 MSKCC, 5 Weill Cornell Medical College Background: Chronic hepatitis B virus (HBV) infection is a global health problem causing significant liver disease and hepatocellular carcinoma

TB-500 is a 17-amino-acid synthetic fragment of Thymosin Beta-4 (T4), a 43-residue actin-binding protein

Jiang ZH, Wan XL, Lv GL, Zhang WW, Lin Y, Tang WQ, Wei HY, Ou FQ, Shi YL, Yang YC, Liu J, Chan CHF

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