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The extrinsic pathway is started by death receptors and involves the activation of caspase-8, which directly activates caspase-3, causing apoptosis

(33) demonstrated that activation of microglial NLRP3 inflammatory vesicles by diabetic mice and BV2 cells via the ROS/JNK MAPKs/NF-B pathway leads to neuroinflammation

As reported, 60% of the daily intake of arsenic, including inorganic and methylated, is eliminated in the urine, making the kidney a target organ 17

Occupational risk factors for renal cell carcinoma: agent-specific results from a case-control study in Germany

Mirror-image gene transcription and reverse transcription