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10.1016/j.lfs.2014.06.003 90 VijayvargiyaP.CamilleriM.ChedidV.MandawatA.ErwinP

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Is S-acetyl-glutathione (SAG) better than regular glutathione

The main CYP isozymes catalyzing the metabolism of the majority of drugs presently in the market and other xenobiotics are arranged into three gene families (CYP1, CYP2, and CYP3) based on their amino acid sequence homology (Nebert, Inter-individual and inter-ethnic variability in drug response and adverse reactions, has been attributed in part, to the polymorphism of CYP genes , including CYP1A1, CYP2A6, CYP2A13, CYP2C8, CYP2D6, CYP3A4, and CYP3A5 (Gonzalez, genes among different ethnic populations (Ingelman-Sundberg et al., Stress Impact on CYP-Dependent Drug Metabolism The majority of the CYP genes are inducible and regulated by several external and internal factors, which, as a result, may also influence the fate and effects of drugs through modified enzymatic activity

This work was supported by the Fundao de Amparo Pesquisa do Estado da Bahia (FAPESB, Brazil - Bioprofar-BA, PIE0001/2024