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Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, et al

In humans, alterations in the normal functioning of these efflux pumps are implicated in the etiology of diseases such as DubinJohnson syndrome 7 and cystic fibrosis 8,9,10

Membrane modification strategies include covalent conjugation methods, such as bioconjugation and click chemistry reactions, as well as non-covalent approaches like multivalent electrostatic interactions or receptor-ligand binding

Using an untargeted NMR-based approach, we identified and quantified 44 metabolites from a total of 52 detected (Figure S1, Table S1), excluding those with poor signal quality in the H-NMR spectrum or technical artefacts such as residual methanol

Huang et al., 2000a)