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Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPAR signature

Meanwhile, SAHA could block the compensatory upregulation of SCL7A11 induced by Erastin treatment alone and improve the efficacy of the drug [197]

As metabolites are the substrates used to generate chromatin modifications, including methylation and acetylation modifications of histones, a complicated interaction exists between metabolism and epigenetics