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A recent prospective study using data from 585 279 participants found that elevated baseline levels of inflammatory markers, including CRP, were prospectively associated with an increased risk of developing affective and psychotic symptoms over a 30-year follow-up period [8 ]

Clinical Chemistry 44(6), 13091315.CrossRefGoogle ScholarPubMed Cao, G, Alessio, HM & Cutler, RG (1993) Oxygen-radical absorbance capacity for antioxidants

Genes , 16 (4), 441

This occurs when alcohol metabolism is disrupted, leading to a buildup of acetaldehyde, which causes toxic effects

Although these studies reveal the therapeutic potential of TFEB, clinical validation is incomplete because of limited pharmacokinetic data and uncertain long-term effects