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2024 May 10;43(5):114226

Analysis of the large VITATOPS study, which was a cohort of 1,400 participants expanding over 10 countries, found a significant reduction (~4 mol/L) in homocysteine in the group receiving vitamin B12, folate, and vitamin B6 supplementation compared to the control (29, 30)

Nutritional risk factors, microbiota and Parkinsons disease: what is the current evidence

The demonstration of L-glutamate-stimulated release of L-homocysteic acid from astrocytes is further evidence that their activity is largely glial-based