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The association of increased ROS production with enhanced detoxification and antioxidant activity of hepatic steatosis, but not with NASH, indicates that in NASH, the ROS overproduction mechanism may be inadequate [44]

doi: 10.1093/neuonc/now135

Lack of therapeutic response Verifying quality: Independent testing most definitive

lower salivary cortisol, amylase, blood pressure, and subjective stress ratings (Lopresti 2022)

Experimentally, peripheral administration of LPS in animals induces microglial activation and can exacerbate amyloid pathology and neurodegeneration [62]