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Because NGF induces an antioxidant response via TrkA/Akt or MAPK signaling pathway, these data support our previous finding that increased levels of GSH in the brain are associated with ERK2 activation ( Our findings suggest that systemic NGF helps to maintain redox homeostasis, which would explain why NGF and TrkA levels are increased in both the plasma and brain during the systemic oxidative stress generated by physical activity (Ang et al., 2003

Free radicals are formed by the normal processes of the body and are increased with chemical and environmental exposure to toxins

VEGF plays a pivotal role in angiogenesis, the formation of new blood vessels, which is critical for delivering oxygen and nutrients to healing tissues while eliminating metabolic waste

demonstrated that overexpression of fibroblast growth factor 21 (FGF21) markedly reduced myocardial 4-HNE accumulation

Creatine diet supplement for spinal cord injury: influences on functional recovery and tissue sparing in rats