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Redox balance is the equilibrium between oxidative stress (damage) and antioxidant defense (protection)

It is responsible for most of the antioxidant and detoxifying functions of Glutathione

That study revealed that ferrylHb but not Hb or metHb induce active IL-1 production in LPS-primed macrophages in an NLRP3-dependent manner ( Hemorrhage-Associated Macrophage Subsets Besides the two extreme canonical macrophage phenotypes, the pro-inflammatory M1 and the anti-inflammatory M2, many other specific and distinct macrophage subsets exist (103)