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These findings support previous reports implicating type I and type II IFN dysregulation in psoriasis (73, 74) and PsA (75) that may be the target of therapeutic interventions, e.g

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Moreover, dysregulation of CYP51A1 has been implicated in a wide spectrum of diseases, such as cancer, cataracts, Antley-Bixler syndrome, autoimmune disorders, metabolic liver disease and neurodegeneration

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ROS-responsive materials can undergo physical and chemical degradation if they contain ROS-induced degradable moieties such as thioacetal and thioketals, arylboronic ester, oligoproline, or aminoacrylate