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Additionally, the activation of microglia and astrocytes in ALS leads to the production of ROS and pro-inflammatory cytokines, further exacerbating oxidative damage and motor neuron degeneration [170]

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Under DSHEA, manufacturers can sell glutathione capsules, tablets, or powders without submitting safety data to the FDA as long as the product contains ingredients with a documented history of safe use prior to 1994 or meets the New Dietary Ingredient (NDI) notification process

14 Another study showed that four months of daily oral glutathione supplementation, combined with lifestyle improvements, produced positive effects on liver health in some individuals with non-alcoholic fatty liver disease (NAFLD)