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Later complications may include arthritis or epididymo-orchitis, spondylitis, neurobrucellosis, liver abscess formation, and endocarditis, the latter potentially fatal

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Furthermore, compared to CPZ treatment, there was a significant increase in MBP expression with CPZ + cytokine treatment (104.8% 8.27%, p = 0.015) and CPZ + LPS treatment (107.67% 9.0%, p = 0.008) (Figure 1D)

Although there are no human clinical trials on optimal dosing, we rely on animal literature and anecdotal evidence

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