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Evidence indicates a correlation between inflammatory markers in the airway and airway remodeling, as assessed by sputum neutrophils, eosinophils, or sputum eosinophil cationic protein, demonstrating a significant correlation with airway thickness on CT examination or basement membrane thickening from biopsy results (136, 137)

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Because GSH is subject to non-specific oxidization to ophthalmic acid, a toxic desulfurated analog of GSH, particles/flakes of GSH which are not intimately bound to ascorbic acid crystal particles are more subject to oxidation, and can degrade the product over time

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