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Therefore, exposure to foreign antigens from the first stimulus or to EBV viral antigens leads to activation of CD4 T cells and IFN- release, provided that the cells presenting these antigens to CD4 T cells are not previously infected with EBV, since the gp42HLA-II complex in these cells would prevent their activation [171, 194]

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10.3390/ijms26083915

NoceAMarroneGDi LauroMVitaCMontaltoGGiorginoGet alPotential anti-inflammatory and anti-fatigue effects of an oral food supplement in long COVID patients