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Naltrexone, originally developed for opioid and alcohol addiction, blocks opioid receptors in the brain's reward pathways

The absorbance values were detected at 450 nm using a spectrophotometer Multiskan FC (ThermoFisher Scientific Inc., Waltham, MA, United States)

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To receive this designation, preliminary clinical trials should offer substantial treatment advantages (i.e., safer or more effective) than existing options