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Rumen microbiome associates with postpartum ketosis development in dairy cows: a prospective nested casecontrol study

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GluN2A and GluN2B dominate in the mammalian higher brain structures such as the cortex, and it is well known that there is a developmental switch for NMDAR GluN2 subunits during postnatal development [6], which leads to a change of NMDAR subunit composition from GluN2B to GluN2A subunit-dominant receptors in most brain regions including the cortex, particularly at synapses

show coherence and consistency across animal models, which lends additional confidence in findings (117)