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Previous studies have shown that high-mobility group box 1 released from necrotic IECs causes liver damage during HS by activating the inflammasome [105]

Relevance of Alternative Routes of Kynurenic Acid Production in the Brain

Of note, these three OXPHOS-inducing primary samples all exhibited bi-allelic TP53 mutations without other AML-driver mutations (Supplementary Table 1E)