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Down-regulating TF and TFR1 mainly achieve this effect after ICH

In dogs, ensuring good B12 status might help maintain nerve conduction and brain energy metabolism

Mullick, F

In compliance with the relevant FDA and EMA guidelines [911], for each of the two test liquid formulations, bioequivalence was concluded if the 95% CIs for the estimated test/reference ratios of geometric means of AUC 0-t and C max were within the standard pre-specified acceptance range for bioequivalence (0.80-1.25)