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84,85 In a crossover study of healthy dogs taking the steroid prednisolone, SAMe supplementation at 10 mg/kg body weight twice daily for 42 days was found to reduce blood markers of liver oxidative damage, although the dogs still developed signs of steroid-induced liver disease

Light Snack Small amount of food crackers, fruit, or a light appetiser

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[77] demonstrated an increase in cortisol and pro-inflammatory cytokines (which are able to induce MT expression) in the adipose tissue of people with obesity

Clissold and Brogden, 1985