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Patients often report a glow or fresher look to their skin after a few sessions, but actual visible lightening of pigmentation issues tends to appear after several weeks

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In light of these intracellular observations (Kokame et al, 1996), we hypothesize that changes in the intracellular redox state associated with elevated homocysteine levels can alter the expression of multiple genes involved in other specific cellular functions that could be partially responsible for vascular disorders associated with moderate hyperhomocysteinemia